News Express | Naica crystal digital PCR System focus on precision medicine with the BIOON

Precision Medicine is an approach for disease prevention and treatment, that takes into account differences in personal genetics, environment and lifestyle.

With the emergence of EGFR-TKI-based targeted meidicines, how to use targeted medicines to develop the best therapy is a common challenge faced by all clinicians, and has become a hot spot in the field of research.

How to use the advanced nucleic acid absolute quantification technology to detect mutations related to diseases personally ? The Naica^TM crystal digital PCR system and BIOON present a great description on precision medical technology.

Please pay attention to the BIOON Special Topic for more information：http://www.bioon.com/z/Cycloud_2018/

The Naica^TM crystal digital PCR system

The Naica^TM crystal digital PCR system uses the innovative Droplets in chip microchip technology, known as the microfluidic chip digital PCR system. Crystal digital PCR technology is the core of the next generation on nucleic acid absolute quantification from Stilla technologies, France. The technology uses cutting-edge microfluidic technology to integrate the next-generation digital PCR technology into a single Sapphire chip, and received several technical innovation awards such as the MIT Innovation Award and the French Innovation Award.

The PCR reaction solution is divided into uniform ~30,000 effective droplets by a patented limiting gradient capillary microfluidic network in Sapphire chip, and a 2D compact single layer matrix is formed, which is called crystal digital technology. After the integration of the partition and PCR thermal cycler, the Sapphire chip was quickly scanned to detect droplets containing the amplified target nucleic acid. The number of positive and negtive droplets was calculated by a top-designed Miner analysis to accurately extract the absolute copy number of nucleic acid. The entire process requires only one manual loading operation, which is easy to use and user friendly.

Naica^TM crystal digital PCR system combines powerful image analysis with intuitive visual inspection, provides unparalleled confidence in the absolute quantification of nucleic acids in digital PCR technology to generate the true data you can trust. It only takes 2.5 hours to get results.

· Easy to use

· Sapphire chip, top microfluidic industrial design

· Crystal digital PCR technology to meet the absolute quantitative application requirements of nucleic acid